Sunday, June 28, 2015

Can chemotherapy kill Lyme?

Of course, as I prepare to complete the ABVD chemotherapy for Hodgkins, the question that remains is

Can chemotherapy kill Lyme?

If so, I may be "lucky" to have found a cure for my Lyme infection.  Or, as they say, "Killing two birds with one stone."

Coincidentally I was sent an article today titled "Researchers' discovery may explain difficulty in treating Lyme disease." In the paper published in the Journal of the American Society for Microbiology, the researchers note that an anti-cancer drug completely eradicated lyme "persister cells" in a single dose.  It is these persister cells that has made antibiotics, even combination treatments, ineffective against the lyme bacteria.

So perhaps there's hope that coming out of this I shall be both cancer-free and lyme-free…

Reference:

Borrelia burgdorferi, the causative agent of Lyme disease, forms drug-tolerant persister cells. Bijaya Sharma1, Autumn V. Brown1, Nicole E. Matluck1, Linden T. Hu2 and Kim Lewis1*
1 Department of Biology, Northeastern University, Boston, Massachusetts, USA;
2 Department of Medicine, Division of Geographic Medicine and Infectious Diseases,
Tufts Medical Center, Boston, Massachusetts, USA.

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